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In the first section of this page, you will write a daily summary of that day's class. For example in your chapter 2 blog, your first entry should be titled 9/3/10. You should then write a one or two paragraph summary of that day's lecture, outlining the major points. In the second section, you are required to add two items (link to a website, video, animation, student-created slide show, student-created PowerPoint presentation) and one journal article pertaining to a topic in this chapter. A one-paragraph summary must accompany each item describing the main idea and how it applies to the lecture topic. Please see the PBWorks help guide for assistance embedding video and other items directly in the page. I will also produce a how-to video on using tables to wrap text around items and other useful tips. Please see the syllabus for organization and grading details.
A. Daily Blog
9/22/10
Today, we went over cells and the essential organelles that are found in each. There are two types of cells: prokaryotes and eukaryotes. Prokaryotes have no nucleus and no membrane-bound organelles. Eukaryotes have bigger cells and compartmentalization. Cells do not have the same abundance. Ribosomes are in charge of protein synthesis, cytoplasm is the fluid in the cell that moves things around and is the site of chemical reactions, and the plasma membrane regulates things that go in and out of the cell. Genome is the entirety of DNA and proteome is DNA that is expressed. The endomembrane system keeps everything out of the cytoplasm, creates vesicles used for transport, and shuttles cargo throughout the cell. The ER consists of rough ER and smooth ER. The rough ER has ribosomes on it and its function is protein synthesis. The smooth ER is a factory for lipid production. The Golgi apparatus uses vesicles to transport materials between stacks. Their function is secretion, processing, and protein sorting. Pulse-Chase experiments were used to trace the path of radioactive proteins.
9/24/10
Today, we learned about protein-trafficking. In the rough ER, co-translational modification takes place. They help modify secretory and membrane proteins. In the cytoplasm, there are free ribosomes which hold amino acids that form proteins. Semi-autonomous proteins are modified by post-translational modification. DNA produces mRNA and this is called transcription. Protein synthesis is called translation. The N-terminus translates into the C-terminus. The ER signal sequence tells the proteins where to go, then the SRP binds to the protein and shuttles it to the ER.
This is a video about the process of protein-trafficking. Proteins from the rough ER are sent to the Golgi apparatus through vesicles. While passing through the Golgi, enzymes attach to proteins to direct them to where they should go. Vesicles leave the Golgi and go to where they are needed.
This is a video that shows vesicle traffic inside plants. A plant's hair roots grow rapidly and that requires the cells to deliver membrane and cell wall material rapidly using vesicles. In the video, the vesicles are shown in green and you can see them moving rapidly back and forth.
This article is about how SRP might not be the only thing that delivers mRNAs to the ER. There might actually be mRNAs that are full time residents of the ER membrane.
Chapter 4 Blog: General Features of Cells (Philip)
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